Another choice of intra articular injections for the treatment of osteoarthritis, is injections of hyaluronic acid. Hyaluronic acid is produced by the body. It concentrates on the joints (as in other places), however, in people with osteoarthritis it breaks down, resulting in their pain and stiffness. It is an alternative for those who are not relieved by non-steroidal anti-inflammatory drugs or who can not take them because of kidney or stomach problems. Laboratory and clinical studies suggest that hyaluronic acid can do much more than just lubricate the joint.
Studies show that hyaluronic acid infusion inhibits prostaglandins and cytokines, which promote inflammation at the cellular level. It can also cause increased production of this important substance, which can in turn help maintain cartilage. The beneficial effects of injections of hyaluronic acid last from 6 months until a year accordingly. After this time administration should be repeated.